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88 Lymphoma models have also demonstrated a negative impact of CD55 and CD59 on daratumumab activity, which may be a prevalent resistance mechanism
Altered B12 handling and reduced clearance in kidney disease, and both cellular release and reduced clearance in liver disease, can raise B12, so supportive renal or hepatic findings make those causes plausible
Smith, A
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[DOI] [PubMed] [Google Scholar] 145.Tan NS, Shaw NS, Vinckenbosch N, Liu P, Yasmin R, Desvergne B, et al
22 Liu, H.-L
