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Study population We initially included 10,585,844 Korean adults aged 20 years or older who had participated in NHSP in 2009 from the NHIS database of the entire Korean population

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Skin Penetration and Depot Formation An ex vivo human skin penetration study measured a permeability coefficient of 2.43 x 10^-4 cm/h for copper tripeptide, with 82 micrograms per square centimeter retained in dermal tissue as a depot over 48 hours (PMID 20703511)

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