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This product's NTS was calculated using a combination of the following derived values - Rating Live Date 12 Jun 2026 Rating Expiry Date 12 Jun 2027 Details about our Testing & Rating process can be found here LAB TEST RESULTS & METHODOLOGY We tested this product at multiple labs

While hydration affects urine concentration, it does not speed up the body's elimination of EtG

longum and 120 mg of FOS

10.1038/emm.2015.122 52 HehreE

The positive transcriptional regulatory factors CLOCK (CLK) and CYCLE (CYC) form heterodimers that lead to the transcription of the negative regulators PERIOD (PER) and TIMELESS (TIM) via binding to E-boxes in their promoters 7,8

PMID: 32720683 Chang M, Russo GS, Canseco JA, Nicholson K, Sharma R, Koomson J, Vaccaro A.R