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Description
Under glucose-deprived conditions, the knockout of IDH1 or ME1 significantly reduces the NADPH/NADP+ and GSH/oxidized GSH ratios, leading to elevated ROS levels and increased cell death in cancer cells (94)

Matschke, J

One SAE reported after 12 weeks of treatment with l glutamine as sickle cell hepatopathy (SCH) completely recovered and withdrawn from the study

10.3389/fmicb.2024.1305617 21 HuangR.et al (2024)

Cell Death Dis 13:113

10.1128/AAC.22.4.611 39
