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Recent studies have also highlighted the role of -syn propagation in spreading pathology across brain regions, further complicating the disease progression (Shin et al., 2023)
Some medicines work through the same pathway

Theor Appl Genet 138:115

Cn dng lu di t c hiu qu nh mong mun
Al-Sahlany, S
The current investigations found a significant decrease in serum insulin and an increase in glucose levels