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Rotenone blocks the electron transport chain complex I which in turn causes mitochondrial dysfunction via increased levels of Cyt-c, disruption of the mitochondrial membrane, and oxidative stress 38

[DOI] [PubMed] [Google Scholar] 30

News Release April 03, 2002 More than one in five weight loss, slimming and/or diabetes supplements fail ConsumerLab.com evaluation Problems found in chromium and pyruvate products

Overall, only three studies were deemed of good quality

I don't see any benefit yet

Diep, P
