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Once the weekly milligram target is set, reconstitution determines only the concentration and syringe draw not the dose itself

5 Benefits of Hydroxocobalamin: Restoring B12 levels Hydroxocobalamin is effective in treating macrocytic anemia associated with vitamin B12 deficiency, particularly in conditions such as pernicious anemia and malabsorption syndromes

Larson EB, Shadlen MF, Wang L, et al

However, researchers acknowledge they are far from developing a clinical application

[16] There is no advantage to the use of adenosylcobalamin or methylcobalamin forms for the treatment of vitamin B 12 deficiency