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The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )
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Indeed, cyanocobalamin treatment did not increase IL-12/23p40 protein levels in germ-free C57BL/6J mice (Fig
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