glutathione peroxidase 4 a new player in neurodegeneration Ablation of ferroptosis regulator forebrain neurons promotes cognitive impairment and Glutathione peroxidase 4 (GPX4) |
Description
10.1073/pnas.1301218110 Proc
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N
Epstein CJ: Down syndrome (trisomy 221)
An estimated 15 g whole cell extract was loaded per well on 10%-12% SDS-PAGE gel and transferred onto nitrocellulose membrane (Bio-Rad)
Although further study is necessary to understand the reason for the lack of growth factor receptor responses in some but not all GPx-1-deficient cells, the end result of these attenuated pro-survival pathways would be decreased cell growth and augmented apoptosis
make claims regarding outcomes or efficacy
