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The transfection of pHDAC2 combined with the elimination of ROS by MnPD exhibited a significant enhancement of intracellular HDAC2 expression levels, suggesting that the multi-antioxidative activity of MnPD plays a crucial role in the expression of HDAC2

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Most (8085%) of the cellular GSH are in the cytosol, 1015% is in the mitochondria and a small percentage is in the endoplasmic reticulum [68]

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