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NO donors SNP and nitroglycerin have a long history of use in cardiovascular medicine for their vasodilatory effects [266,267] and other agents such as NO-releasing aspirin (NCX 4215) have also been observed to exert antithrombotic effects [268]

doi: 10.1093/oxfordjournals.molbev.a026159 128 HoltenE

doi: 10.1016/j.endinu.2018.03.012 97 CerneaSRazI

The significant decrease in ROS-mediated tube formation and wound healing in human microvascular endothelial cells (HMECs) after siRNA-mediated NOX4 knockdown further underscores its crucial role in angiogenesis and endothelial cell proliferation [51]

[DOI] [Google Scholar] Smrek J