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mRNA methylation is emerging as a key mechanism involved in translation, splicing, export and degradation, and dysregulations in the process lead to the development of various diseases, including melanoma, leukemia, pancreatic and liver cancer, etc

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By degrading the target, PROTAC 19 reduces AKT protein phosphorylation and leads to increased p53 expression 81

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Shoutouts to the amazing pitchers
