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The rationale for combining them is mechanistic

All the authors are eligible to be an author as per the international committee of medical journal editors (ICMJE) requirements/guidelines

Emphasizing Mandatory Screening Mandatory screening for PN, like retinopathy evaluation during type 2 diabetes diagnosis, should be emphasized, considering surprising statistics that reveal up to 62% of patients with idiopathic PN exhibit prediabetes [36]

When the right peptide binds with the right receptor, it triggers a specific function, such as releasing hormones, burning fat, or increasing metabolism

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Additionally, the lack of sensation in the feet, often overlooked by patients, can lead to insensate injuries, falls, foot ulceration, and even amputation, underscoring the urgent need for early identification and intervention [2, 14,15,16]