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The preservation of proteostasis plays a crucial role in cell survival and becomes even more important for nondividing cells such as neurons, whose proteostasis machineries are reduced with aging, causing an accumulation of damaged organelles and misfolded proteins (327329)

Complex genetic interactions between DNA polymerase and the NHEJ ligase

The participants gave written informed consent for the publication of this paper in its current form

This characteristic has been utilized to enhance inhibitory control in children, particularly those with attention-deficit/hyperactivity disorder (ADHD) (Chang et al., 2014)

The size of the LDs is a factor that conditions whether an LD (a) is targeted by microautophagy and digested piece by piece as parts of larger vesicles are pinched off and trapped inside of double-membrane vesicles or (b) is targeted by macroautophagy and digested in lysosomes as a whole small vesicle [82]

In conclusion, as we stand at the crossroads of stem cell biology and translational medicine, MSCs embody both the promise and complexity of regenerative therapies