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E.de LimaM.NascimentoD

(CPMP/EWP/2339/02)

Deglutathionylation of Cys sulfenic acid forms a disulfide bridge that can transmit the signal of oxidative stress and influence the transcriptional factors (Fig
Wang W, Hu Y, Yang C, Zhu S, Wang X, Zhang Z, et al

About half the cysteine used for glutathione synthesis is produced by the trans-sulphuration pathway [33]

Therefore, increasing glutathione levels may protect these neurons from further damage, reducing the severity of Parkinson's disease
