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Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was financially supported by the National Natural Science Foundation of China (82003755) and the Initial Scientific Research Foundation for Youth of Jinhua Municipal Central Hospital (JY2019-2-01)

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Its ligand RMSD also remained consistently low, approximately 1.5 , indicating a stable binding mode comparable to that of istradefylline

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Tanner and Goldman 1996)