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Since carnitine enhances mitochondrial function, it is plausible that the reduced fatigue levels observed in the present study were mediated by carnitine-driven improvement in mitochondrial function

Intermittent claudication is a warning of systemic atherosclerosis and is considered an independent risk factor for cardiovascular morbidity and mortality [48]

Therefore, to properly improve and establish the clinical beneficial effects of high doses of L-C in CAD patients, further long-term and large-scale intervention studies are needed

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