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Neurofibromatosis type 1 (NF1) (Online Mendelian Inheritance in Man [OMIM] #162200) is the most frequently occurring neurocutaneous syndrome

Genomics 2013, 6, 44

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*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Dysbiosis-driven aberrations in microbial composition and activity disrupt the production of these metabolites, compromising intestinal barrier integrity, fueling chronic low-grade inflammation, and exacerbating insulin resistance