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Supplementary material The Supplementary Material for this article can be found online at: References Akiyama S., Fukuda S., Steinberg J

The ER-mitochondria interface, where Ca(2+) and cell death meet

These include a double blinded, randomized, placebo-controlled Phase IIb trial(Beydoun et al., 2015

Pesticide risk mitigation by vegetated treatment systems: A metaanalysis

G1 length was found to nearly double during neural SC differentiation, and enabled purification of SCs from heterogeneous cell populations [13]

However, although this approach decreased tumour cell proliferation and, consequently, tumour volume in an NF1 mouse model, 42,43 mTOR inhibitors were ineffective against pNF in one clinical trial 44 but prolonged progression-free survival, albeit modestly, in another trial 45 (NCT00634270)