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However, there is an indication that GSH can also act as a modulator of DNA-repair activity

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Brauner et al compared children treated with craniospinal irradiation to those receiving cranial irradiation alone with height SDS being significantly lower in the craniospinal group at 1.46 SD compared to the cranial irradiation only group with a height SDS of -0.15 (221)

This makes it difficult for it to penetrate the deeper layers of the dermis where melanin production actually happens

10.1016/j.chemosphere.2017.04.027 121