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[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Poletti S., Paolini M., Mazza M.G., Palladini M., Furlan R., Querini P.R., Benedetti F

BMC Genomics 6 , 145

Humoral stimuli refers to the control of hormone release in response to changes in extracellular fluids such as blood or the ion concentration in the blood

Replenishing the nutritional status of the host by increasing vital amino acids such as cysteine to enhance GSH levels and selenium to improve selenium deficiency and facilitate selenoprotein (GSH peroxidases, thioredoxin reductases) expression can inhibit oxidative stress, modulating inflammation, suppressing endothelial dysfunction, and protecting vascular cells against apoptosis and calcification (He et al., 2017

Salehi et al., 2019a), even if the real effect is still debated (Panic et al., 2017)