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2016;27:vi359

Lambadiari V, Mitrakou A, Kountouri A, Thymis J, Katogiannis K, Korakas E, et al

EGFR-siRNA molecules with negative phosphate groups could bind very efficiently to the positively charged surface of AuNPs-TMC via electrostatic interactions in an optimized weight ratio

Gradient of pH can be generated by using ionophore, which is another versatile approach for encapsulation

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PMID 12773329
