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Increased levels of peroxynitrite are associated with tumor progression

Two main pathways can trigger this process, the intrinsic, also called mitochondrial pathway, when apoptosis is initiated by the internal signals of mitochondrial origin, and the extrinsic when apoptosis is activated by external stimuli [16]

The mean total dose of botulinum administered to the buccinator per session was 2.0 units (range, 0.62.5 units) [34]

301 To summarize, MTs possess a wide-ranging and complex ability to regulate inflammatory responses

Treatment with ZNT restored redox balance, preserved mitochondrial integrity, prevented DNA damage and apoptosis, and normalized angiogenic gene expression

(An, Vaccaro, Cotler, Lin)