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Two-dimensional nanoclays Two-dimensional nanoclays consist of alternating tetrahedral and octahedral sheets, characterized by large surface areas and favorable adsorption properties for drug delivery [293]

However, the exact onset mechanisms are not fully elucidated
However, this extrapolation from one organ to another is questionable as the exposure levels, the phase I metabolic capacity to generate NAPQI, the phase II metabolic capacity to eliminate APAP, and potential adaptive mechanisms in response to an APAP-induced cellular stress are not well described in the CNS system

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doi: 10.1016/j.redox.2016.12.022 127 HanYXuXTangCGaoPChenXXiongXet al

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