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Atesidorsen is a 20-mer ASO that has been modified to enhance its stability and circulating half-life

[PubMed 16030359] 2632

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Sequence: Gly-His-Lys (3 amino acids) complexed with Cu(II) Molecular formula: C14H24N6O4Cu Molecular weight: 403.92 g/mol Copper content: 14-16% by weight Blue lyophilized powder (color indicates proper Cu(II) coordination) HPLC and mass spectrometry verified 100 mg larger format for extended research protocols For laboratory research only

However, some studies have observed nicotine-independent and flavour-independent effects which mainly were attributed to aldehydes generated during the heating of E-cigarette liquid, most notably acrolein [68]