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Together, these data indicate divergent cell-specific regulation of Kv4 channel subunits, and suggest that neuroadaptations in Kv4 channels may be an important factor underlying altered synaptic plasticity, poor cognitive performance, and aberrant excitability associated with prolonged alcohol exposure and withdrawal

On the other hand, acetyl L-carnitine is frequently positioned as a cognitive enhancer and neuroprotective agent, targeting an older demographic or those interested in brain health

Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells

J Biol Chem 283(49):3387433882

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