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[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Arning J., Dringen R., Schmidt M., Thiessen A., Stolte S., Matzke M., Bottin-Weber U., Caesar-Geertz B., Jastorff B., Ranke J

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APOE in the brain is primarily expressed by astrocytes and microglia, cell types that are now widely appreciated to play key roles in the pathogenesis of AD

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207,212,217,218,219,220 However, over the past three years, Mendelian randomization studies have utilized genetic variants associated with serum uric acid levels, identified through genome-wide association studies (GWAS), to construct genetic risk scores

Liu CC, Yamazaki Y, Heckman MG, Martens YA, Jia L, Yamazaki A, Diehl NN, Zhao J, Zhao N, DeTure M, et al