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De Chiara F, Ureta Checcllo C, Ramn Azcn J

Parkinsons disease has a higher prevalence among males due to the methylation profile of sex-specific genes such as microtubule-associated protein tau (MAPT)

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Funding The authors disclose receipt of the following financial support for the research, authorship, and/or publication of this article: the grant (01.13.0315.00 - DendePalm Project) for this study was awarded by the Brazilian Ministry of Science, Technology, and Innovation (MCTI) via the Brazilian Research and Innovation Agency (FINEP)

Bioaccessibility and bioactive potential of different phytochemical classes from nutraceuticals and functional foods

Synaptic terminal glutamate-induced Ca 2+ transients activate neuronal nitric oxide synthase (nNOS)-mediated NO generation, and additionally, Ca 2+ overloaded in the mitochondria induces O 2 /H 2 O 2 generation which can lead to ONOO production and excitotoxicity [18,19,20]