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These results highlight the potential of coumarin-loaded PEGylated PLGA nanoparticles as a robust drug delivery system for addressing bioavailability and permeability challenges associated with neurodegenerative disease treatments 135

In addition, aged WM becomes more susceptible to neurological disorders, such as stroke, traumatic brain injury (TBI), and neurodegeneration

While antinutrients are often regarded as inhibitors of nutrient absorption with potential adverse health effects, emerging evidence suggests they may also confer neuroprotective benefits under specific conditions

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We further stained for CUX1 as a marker of layer II/III neurons which can be vulnerable to TDP-43 pathology in FTD and degeneration in Alzheimers disease

Available from: [DOI] [PubMed] [Google Scholar] 140.Foulds P, Mann DMA, Mitchell JD, Allsop D