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Description
Human behavioral studies have shown that lower levels of plasma and peripheral OXT are found in patients with depression, SZ, and ASD [139,140,141,142]

2022 Jun 30;10:802285
Some protocols split the daily dose into two administrations (morning and evening) to maintain more consistent plasma levels, though definitive human PK data remain sparse as of 2026

As such, different research areas are being explored (Figure 5)

Mestres J, Gregori-Puigjan E, Valverde S, et al

Biopsychosoc Med
