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Experiments with fasted and calorie-restricted rats showed increased mRNA concentrations of acyl-CoA and CPT-1 in the liver, heart and kidneys compared to control animals due to upregulation of PPAR [111]

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Wardenaar FC, Ceelen IJ, Van Dijk JW, Hangelbroek RW, Van Roy L, Van der Pouw B, De Vries JH, Mensink M, Witkamp RF

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Partial reversal was obtained by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid [144]

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