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Researchers identified the upregulated expressions of active caspase-1, active N-terminal fragments of GSDMD (GSDMD-NT), IL-18 and IL-1 in the kidneys of db/db mice (119)

We review the pharmacological and non-pharmacological treatments that can improve mucociliary clearance, reduce airway inflammation and tackle airway infection, the key pathophysiological features of bronchiectasis

Sepsis and other severe illnesses leading to multiple organ dysfunction results from nitric oxide and peroxynitrite generation leading to oxidant injury in a glutamine-deficient environment