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3,21 Children with FH should preferably be reviewed by a paediatrician with expertise in lipidology

(PubMed) Andres M, Sivera F, Falzon L, Buchbinder R, Carmona L

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[Note: This structure is called CURL, the compartment for uncoupling of receptor and ligand.] [5] The receptors can be recycled, whereas the lipoprotein remnants in the vesicle are transferred to lysosomes and degraded by lysosomal acid hydrolases, releasing free cholesterol, amino acids, fatty acids, and phospholipids