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Together, these processes lead to chronic systemic and airway inflammation, pulmonary tissue damage, and respiratory insufficiency

Concluding Remarks and Future Directions According to the latest data, worldwide studies of AD emphasize the need for a multifunctional and systemic approach to studying the pathogenesis of this disease

We next confirmed the production and secretion of several hepatic proteins

Poorly regulated blood pressure in turn, accelerates kidney damage, creating another feedback loop where hypertension worsens the disease progression (Pluznick, 2016)

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First of all, the core proteins that are known to have roles in Wntsignaling in were obtained from literature