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In CD4+ T cell antigen receptor-mediated signaling, the polymorphic regions of the MHC class II proteins engage the receptor complex, whereas the non-polymorphic regions engage the CD4 co-receptor (Parnes, 1989)

Back Laughton, NB, Macallum, AB (1 June 1932) 'The Relation of duodenal mucosa to internal secretion of the pancreas', Proceedings of the Royal Society of London

The route isnt a minor detail

Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystineglutamate antiporter xCT

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Bijalwan S