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Thank you to Dr B

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As a seasoned vegan, Ive heard on multiple occasions I need to supplement vitamin B12 into my diet

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High amounts of homocysteine have also been linked to neural tube defects in early pregnancy

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NNMT inhibition increases cellular concentrations of both substrates that the enzyme would otherwise consume: SAM (the universal methyl donor) and nicotinamide (the NAD + salvage precursor)

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Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action

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[DOI] [PubMed] [Google Scholar] 14

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