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Description
In addition to NAD+, the KP generates different metabolites: kynurenine, kynurenic acid, 3OH-kynurenine, quinolinic acid, anthranilic acid and 3OH-anthranilic acid

10.1074/jbc.M116.722744 J

H.AlatawiA.et al
This results in activation of IL23-producing myeloid cells, which regulate expression of downstream tumour-promoting cytokines, including IL17 and IL6 (103)

Live biotherapeutic products and their regulatory framework in Italy and Europe

Serious adverse events are rare