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Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and insulin resistance on a high fat diet

22 Substitution of the benzamide group of VH45 with a naphthalene moiety yielded 15 , resulting in a tenfold enhanced inhibition (IC 50 = 1.4 0.16 M)

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Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt