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ASC, an adaptor that bridges NLRP3 to caspase-1

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According to Jimnez-Reina et al., one important route involves the activation of phospholipase C (PLC)

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Supernatants were transferred to a new collection tube and dried down (for subsequent glutathione analysis) while the protein pellets were resuspended in 100 l 50% trifluoroethanol (TFE)/50 mM ammonium bicarbonate (ABC) and processed for redox and quantitative proteomics

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