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Common side effects associated with nootropics include: Headaches Nausea Insomnia Anxiety Increased heart rate and blood pressure Additionally, some nootropics can interact with other medications, such as blood thinners, and may not be suitable for individuals with certain medical conditions, including high blood pressure or glaucoma

Additionally, the injection products may contain aluminum which may reach toxic concentrations with prolonged administration in patients with impaired renal function or in premature neonates with immature kidneys

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Statements Author contributions Conceptualization: YX and XJ

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Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury