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In addition, inflammatory macrophages have been shown to activate a senescence programme in dermal fibroblasts 53,59

[DOI] [PubMed] [Google Scholar] 68.Haddad J.J.E., Olver R.E., Land S.C

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Krppel-like factor family genes The Krppel-like Factor ( KLF) family comprises 17 genes in three groups with Cys2His2 zinc finger domain, which binds to the CACCC or GC box DNA elements

Therefore, CLC protein and eosinophil lysophospholipases are distinct proteins.93 Lastly, through its lectin-like domains, CLC protein may bind carbohydrates expressed on microorganisms or biological molecules, such as IgE or laminin.94 Many enzymes, in addition to EPO and the RNases (EDN and ECP), have been identified in human eosinophils, granules, and membranes (see Fig