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TREM2 is essential for microglial clearance of damaged myelin and a loss of TREM2 leads to the downregulation of lipid metabolism genes (Cantoni et al., 2015
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Management of MetS risk factors The metabolic risk variables in the syndromes definition include atherogenic dyslipidemia, elevated blood pressure, high plasma glucose, a prothrombotic condition, and a pro-inflammatory state (45)
To this end, high PSPH expression predicts poor immune checkpoint therapy responses in glioblastoma patients
