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pmid:24297386 60

T cell exhaustion is characterized functionally by a decline in cytokines like interleukin-2 (IL-2), reduced proliferative and cytotoxic capacity, impaired pro-inflammatory cytokine production like tumor necrosis factor, and a decrease in the proliferative potential after antigen exposure in vitro [46,47,48]

Kang S, Krueger GG, Tanghetti EA, et al
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PMID: 21848010
