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But, just like any other therapy, there are some potential side effects
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7,8 Degeneration also results in degradation of the extracellular matrix and loss of hydrophilic matrix molecules, which can lead to structural and biomechanical changes 9 and is a leading cause of increased inflammation, nerve ingrowth 10,11 and release of pain factors
Furthermore, it is able to induce apoptosis independently of cross-linking [58]
However, collagen's role is mostly structural
Ahmad-Mansour N, Loubet P, Pouget C, Dunyach-Remy C, Sotto A, Lavigne JP et al
