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cruzi CH4 strain resulted in the inhibition of growth and metastasis of solid L5178Y-R lymphoma transplanted to BALB/c mice

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However, high-quality safety data in NAFLD populations are limited, and you should consult your GP or hepatologist before starting supplementation to ensure it is appropriate for your individual circumstances and does not interact with any medications you are taking

doi: 10.1093/geroni/igz038.1550 [viii] Sinha, R et al

Caffeine in liver diseases: Pharmacology and toxicology

The downstream effects of the two enzymes are opposite: ACE activity leads to vasoconstriction, oxidative stress, inflammation and apoptosis, whereas ACE2 causes vasodilatation, angiogenesis and anti-inflammatory, anti-oxidative and anti-apoptotic effects [1]