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Antinuclear antibody detection by automated multiplex immunoassay in untreated patients at the time of diagnosis

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FIGURE 4 The CBL primarily catalyzes the cleavage of cystathionine, producing homocysteine, pyruvate, and ammonia

Antiviral activity of phenformin in vivo Given that phenformin is an established drug in humans with known pharmacokinetics and safety profiles, that is hence readily available, we further evaluated the in vivo antiviral potential of phenformin against SARS-CoV-2 in a Golden Syrian hamster model of infection (Fig