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During this meeting, the specialists ensure that the information is clearly understood and emphasize the need for strict adherence and discipline in following the recommendationsparticularly those involving significant changes in diet and lifestylein order to achieve the best possible outcomes

12,13 While certain genetic disorders (eg, Kallmann syndrome) are linked to impaired function of the hypothalamus or pituitary gland from birth, toxic exposures and other environmental factors, both in utero and later in life, are also known to interfere with the activities of the gonadotropic hormones

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