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A "standard drink" in the United States contains around 14 grams of pure alcohol, which equates to a 12-ounce beer, 5-ounce glass of wine, or 1.5-ounce shot of distilled spirits

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Three parameters mainly determine the specific and effective Cre-loxP recombination in vivo : (1) the dose and duration of TAM that determine the activity of the potent metabolites 4-OH-TAM and END, (2) the level of Cre ERT2 expression and (3) the chromatin structure and epigenetic status of the floxed alleles

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[DOI] [PubMed] [Google Scholar] 51.Al-Kuraishy H.M., Al-Gareeb A.I., Al-Maiahy T.J