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These results suggest that 5-amino-1MQ is a potent small-molecule NNMT inhibitor that reverses diet-induced obesity and related T2D

In a previous study bortezomib was shown to alter the metabolic phenotype of sensory neurons and increase the production of metabolites due to aerobic glycolysis, thus resulting in CIPN development

PMID: 33503393

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Passeron T, Lim HW, Goh CL, Kang HY, Ly F, Morita A, et al

& Eltzschig HK Hypoxia and inflammation are two sides of the same coin

Additional studies are necessary to determine which genetic factors underlie susceptibility and the genotypes predisposing to FQAD