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Peer review Peer review information Communications Biology thanks Carla Ferreri, Andrew Hoy, and the other anonymous reviewer(s) for their contribution to the peer review of this work

Bi, A., Wang, Y., Chen, L., Yin, Z., & Luo, L

Although KU-57788 can be used independently to target DNA-PKcs for its anti-tumor effect, it is more commonly applied to synergize with tumors to radiotherapy and chemotherapy drugs [16, 17]

Formaldehyde is widely used in medicine as a preservative agent and also as a precursor for the synthesis of many chemicals

Collectively, these results establish the superiority of the redesigned Grx1-roGFP2 biosensors in terms of expression, fluorescence performance, and functional integrity

Pro-NAC Trial: Combination Therapy with N-Acetylcysteine and Probenecid After Severe Traumatic Brain Injury in Children Given independent neurotherapeutic effects of probenecid [6] and NAC [3], potential synergism of combination therapy [50], favorable safety profiles and FDA approval of both drugs, and the fact that no targeted neurotherapeutics currently exist for treatment of TBI in humans, we embarked on a proof-of-concept, double-blind, placebo-controlled Phase I study of the combination use of probenecid and NAC in children with severe TBI (Pro-NAC Trial